Reverse-Engineering Biological Networks Challenges Caltech Scientists

first_imgEvolutionists love to quote Dobzhansky saying, “Nothing in biology makes sense apart from evolution.”  An article in the current issue of Caltech’s magazine Engineering and Science,1 however, might change that proverb to, “Nothing in biology makes sense apart from information theory and systems engineering.”  The article makes no mention of evolution, but rather looks at biology as a model of complex information processing, computation, control, logic circuits, optimization and error correction.  “TMI, meet IST,” is the title, meaning “too much information meets the office of Information Science and Technology.”  The IST is an interdisciplinary initiative at the prestigious university that draws together mathematicians, information theorists, physicists, biologists, and social scientists with the goal of understanding how information works in complex systems – biological systems providing the guiding example.  It is organized into four new centers, the Center for the Mathematics of Information (CMI), the Center for the Physics of Information, the Center for Biological Circuit Design (CBCD), and Social and Information Sciences Laboratory (SISL), and two old ones, the Center for Neuromorphic Systems Engineering (CNSE), and the Lee Center for Advanced Networking.  “Each new center attacks a basic question,” the article explains.  “Can we find an abstract mathematical description of information that applies across disciplines?  What are the fundamental physical limits to information storage and processing?  How does nature compute and communicate information?  And how does information shape social systems?” (emphasis added in all quotes).    Author Douglas L. Smith opens by wowing the reader with the complexity of a worm.  A tiny roundworm controls its development and biological systems in a manner that staggers the researchers with its precision and complexity.  Smith compares worm information processing to modern intelligently-designed automobiles.  A sedan can contain more than 35 million lines of code in its computers, he says; but that creates a problem for human designers – the cars are getting so complicated, “future development is actually getting stuck because they don’t know how to manage the software.”  Enter C. elegans for a little humility lesson:But Nature controls far more complex mechanisms with ease: Consider the nematode Caenorhabditis elegans.  A lowly roundworm about the size of this comma, it grows from a single-celled egg to an adult containing exactly 959 cells.  The little fellas are clear as glass, and entire generations of lab students have spent countless hours hunched over microscopes tracking the career of each cell.  The whole process takes 24 rounds of cell division—79 of the 959 cells line the guts from mouth to anus, 302 become nerve cells, and 131 die along the way.  “Everything has been mapped precisely,” says [Jehoshua] Bruck [Moore Professor of Computational and Neural Systems and Electrical Engineering, and director of the IST], who has a framed poster of this developmental tree on his wall [the article contains this diagram].  “But we, as engineers, don’t understand how to handle all the information in that map.  We don’t understand what the principles are.”  But, somehow, the cells understand.  The egg divides, and one cell has to call heads and the other, tails.  The process involves the random diffusion of signaling molecules, but the result is very precise—you never end up with a two-headed worm.  Then the other divisions have to follow in the correct order.  “And even when every cell has a clock and the timetable,” Bruck points out, “they still need to coordinate their actions.  It’s like driving on the freeway—sometimes you need to slow down and let another car pass.”  Organisms are just information made flesh.Sidebars in the article provide the history of information theory, from George Boole’s binary algebra to Claude Shannon’s Boolean circuitry.  Information storage and processing, guidance and control of circuits dealing with vast amounts of information under constraints of time or bandwidth, are some of the technical challenges discussed in the article.  The overlap between biological and engineered systems throughout the article is almost seamless, except for the fact that biological systems are vastly superior to anything man has invented so far.  For example,But building complex machinery from molecule-sized parts is no cakewalk—how do you put all those tiny pieces in the right places?  Nature uses a program encoded in the genes.  Inspired by this, [two center members] are making DNA “tiles” that spontaneously assemble into complex patterns based on information contained in the DNA.Cells do amazing things with seemingly slap-dash components.  The body heals broken bones and fights off diseases, and we walk around and we do crossword puzzles, all with flimsy, floppy protein molecules packed into cells that keep dying.  There’s nothing magical about the stuff we’re made of, so clearly the miracles are in the circuits—broadly defined—that they’re organized into.  How do these circuits work?  And what else can be done with the same components? [p. 12]The goal of the Center for Biological Circuit Design (CBCD), says Paul Sternberg, Morgan Professor of Biology, investigator, Howard Hughes Medical Institute, and director of the center, “is to learn about biological circuits by trying to build them.”… There are actually three nested levels of circuitry, says Sternberg: networks of signaling molecules within a cell that handle such things as regulating metabolism or allowing an amoeba to find and engulf its prey; circuits consisting of several cells, such as the ones that coordinate our defense against infection; and the vast neuronal circuits that are responsible for, say, understanding speech.  The CBCD will initially tackle the first two, leaving the brain to the ganglion of neuroscientists on campus.By biological standards, the human brain is only middlingly complex–a protein molecule can have 10 thousand atoms, a cell can contain a billion macromolecules, and the heftier E&S reader might consist of 100 trillion cells.  That’s 27 orders of magnitude of organization from an atom to a person, which is like going from the diameter of an atom to the distance to Sirius [p. 12.  For a visualization, see Secret Worlds: The Universe Within.][Sidebar] A schematic of Arnold’s cellular band-pass filter.  The sender cell emits molecules of ALH… [He describes the complex interactions of seven parts in the cascade].  Got all that?  And this is a very simple regulatory scheme, as things go…. [p. 13].Says Sternberg, “…we’re just trying to get anything to work.”  It helps that the CBCD houses people who are building artificial circuits and people who are reverse engineering real ones.  “Now we say, ‘This cell has switchlike behavior—what mechanism is it using?’  It would be nice if you could say, ‘Well, there are four different ways that cells usually do that.’  It would be even better if you could say, ‘Well, there’s one way that they usually do it, let’s go test that one first.’” [p.13]“Everything we do in CNSE [Center for Neuromorphic Systems Engineering] is IST-related,” says director Pietro Perona, professor of electrical engineering.  “We take neurobiological principles and use them in engineered systems, and use engineering expertise to try to understand the brain.”The Information Age will be as monumental as was the Industrial Age in its effect on society.  Smith wraps things up whimsically:Says Bruck, “In time, I think ‘information’ will be a first-order concept.  So in 20 years, if a high-school student asks her friend, ‘Do you like algebra?’ the other girl will say, ‘Yes,’ or ‘No,’ or ‘Yes, but I hate the teacher.’  But the other day I asked my daughter, a high-school junior, ‘Do you like information?’ and she said, ‘What?!!’”1Douglas L. Smith, “TMI, Meet IST,” Engineering and Science (LXVIII:1/2), [summer] 2005, pp. 6-15.OK, Intelligent Design Movement, charge!  Grab this paper and wave it in the faces of the Darwin Party, and say, “Look!  The future is information, reverse engineering, and treating biological entities as intelligently designed circuitry.  That is what ID is all about.  This entire article had as much use for Darwinism as an astronaut for a pogo stick.  Biological systems could only be understood in terms of their information content, their logic, circuitry and programming—i.e., their design.  The design is so extraordinarily complex that Caltech’s brightest stars are at square one trying to figure it out.  Darwinism is an impediment, an 18th-century, Industrial Revolution paradigm that is not up to the requirements of the Information Age.  Step aside!  ID is the future.”    This article is one of many recent entries at the intersection of biology and nanotechnology that illustrates the power of a design-theoretic approach to science.  Although it does not mention intelligent design (and, undoubtedly, many of the participants are probably evolutionists), the content of the article plays right into the hands of the intelligent design movement.*  Look: a large interdisciplinary scientific enterprise (IST) has been organized with the goal to understand and capitalize on the information content in biology.  The same topics in this article are prevalent in the ID literature: information theory, reverse engineering, understanding and detecting design, programming, circuitry, complexity and communication.  The identity of the Designer, though an important and interesting subject,** did not enter into the discussion, and was not essential for achieving the goals of the IST.  This shows that ID is a non-religious scientific approach; it can bear fruit in a multicultural, secular setting.  Rather than bringing science to a halt, it promotes, stimulates and encourages scientific discovery—findings that will promise to revolutionize society, help cure disease, remove the drudgery of our lives and fulfill the promise of Daniel 12:4 that “many shall go to and fro, and knowledge shall increase.”  It’s past time to remove the ball and chain of Darwinian mythology and speed ahead into the Information Age—the golden age of intelligent design. (Visited 7 times, 1 visits today)FacebookTwitterPinterestSave分享0last_img read more

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Darvish left spinning as Dodgers fall into World Series deficit

first_imgJapan ex-PM Nakasone who boosted ties with US dies at 101 READ: Astros start fast, top Dodgers for 2-1 World Series leadIf Los Angeles is to win the World Series, the Dodgers will have to do it at home for the first time since 1963 — and with a bullpen that has covered 13 1/3 innings over the past two games.FEATURED STORIESSPORTSWATCH: Drones light up sky in final leg of SEA Games torch runSPORTSSEA Games: Philippines picks up 1st win in men’s water poloSPORTSMalditas save PH from shutoutAhead of his start, Darvish joked he should receive a gracious greeting because he wore a “Houston Strong” T-shirt last month to raise money for hurricane relief.“Maybe I can use a ball that doesn’t have much pop in it,” he said through a translator. Don’t miss out on the latest news and information. QC cops nab robbery gang leader, cohort Los Angeles Dodgers starting pitcher Yu Darvish leaves the game during the second inning of Game 3 of baseball’s World Series against the Houston Astros Friday, Oct. 27, 2017, in Houston. (AP Photo/Eric Gay)HOUSTON — Pitching in his World Series debut, Yu Darvish kept turning his head as balls clanked off the outfield wall or soared over it.Darvish had never pitched fewer than three innings in 135 previous big league outings. On baseball’s biggest stage, he got just five outs and left with a four-run deficit in Friday’s night’s 5-3 loss to Houston, which put the Dodgers in a 2-1 World Series hole.ADVERTISEMENT View comments Kammuri turning to super typhoon less likely but possible — Pagasa LATEST STORIES Yuli Gurriel drove a slider into the left field Crawford Boxes opening the second, and Josh Reddick doubled to left for his first extra-base hit in 49 plate appearances this postseason — the third extra-base hit off Darvish among the Astros’ first six batters.Evan Gattis walked and, after a visit to the mound by pitching coach Rick Honeycutt, Gonzalez hit a 373-foot single off the left-field wall for a 2-0 lead.Brian McCann lined an RBI single into right and Alex Bregman hit a sacrifice fly with one out, and Darvish was done for the day, skirting the edge of the World Series logo as he walked to the third-base dugout.Yasiel Puig also had a bad day. With Los Angeles trailing 4-1 in the fourth, he singled down the third-base line, ran past first, slowed to almost a stop, then noticed the ball was bounding off the low wall. He then started for second and was thrown out by Gonzalez.Reliever Tony Watson added his own errant moment, throwing Gattis’ chopper past first baseman Cody Bellinger in the fifth, allowing Reddick to score from first base on what was ruled an infield hit and a two-base error.After a strong start by Clayton Kershaw in the opener and a good-but-abbreviated one from Rich Hill in Game 2, the Dodgers have failed to retire the side in order for 14 consecutive innings. The bullpen stretched a scoreless streak to 28 innings during Game 2 on Wednesday night before blowing a save and losing in 11 innings. Houston had enough pop to keep the ornamental train above Minute Maid Park’s left-field wall sounding its whistle often early in Friday’s game.Darvish threw 49 pitches and had just one swing and miss — by Carlos Correa on a 98 mph fastball in the first inning. There was also a missed bunt attempt by Marwin Gonzalez before his run-scoring single in the second.The 31-year-old Japanese right-hander seemed amped up. His fastball averaged 94.7 mph during the season, according to Brooks Baseball, but with higher velocity against the Astros, his slider flattened.Acquired from Texas at the July 31 trade deadline, Darvish had been 2-0 with a 1.59 ERA in a pair of postseason starts, winning Game 3s against Arizona in the Division Series and the Cubs in the League Championship Series.But he seemed out of sort right from the start against Houston, falling behind leadoff hitter George Springer 3-1 and allowing an RBI double.ADVERTISEMENT Kin of Misamis Oriental hero cop to get death benefits, award — PNP CPP denies ‘Ka Diego’ arrest caused ‘mass panic’ among S. Tagalog NPA MOST READ Astros start fast, top Dodgers for 2-1 World Series lead Read Next Brace for potentially devastating typhoon approaching PH – NDRRMC Trump attends World Series baseball game in Washington DC PLAY LIST 01:04Trump attends World Series baseball game in Washington DC07:50BYS Academy: Create a Fall Glam Makeup Look00:50Trending Articles01:37Protesters burn down Iran consulate in Najaf01:47Panelo casts doubts on Robredo’s drug war ‘discoveries’01:29Police teams find crossbows, bows in HK university01:35Panelo suggests discounted SEA Games tickets for students02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games Stronger peso trims PH debt value to P7.9 trillion Typhoon Kammuri accelerates, gains strength en route to PHlast_img read more

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China, South Korea, Iran open Asian Cup with victories

first_imgHotel management clarifies SEAG footballers’ kikiam breakfast issue PH underwater hockey team aims to make waves in SEA Games PLAY LIST 02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games02:11Trump awards medals to Jon Voight, Alison Krauss Is Luis Manzano planning to propose to Jessy Mendiola? South Korea’s forward Hwang Ui-Jo, center, celebrates after scoring the opening goal during the AFC Asian Cup group C soccer match between South Korea and Philippines at Al Maktoum Stadium in Dubai, United Arab Emirates, Monday, Jan. 7, 2019. (AP Photo/Kamran Jebreili)AL AIN, United Arab Emirates — With coach Marcello Lippi in charge and the team needing a bit of help from an own-goal, China came from behind to beat Kyrgyzstan 2-1 at the Asian Cup on Monday.Lippi, who won the World Cup with Italy in 2006, is trying to win another title in what is likely to be his last major tournament. But it won’t be easy in the United Arab Emirates.ADVERTISEMENT Private companies step in to help SEA Games hosting SEA Games: Biñan football stadium stands out in preparedness, completion Another coaching heavyweight, Sven-Goran Eriksson, lost his opening match of the Asian Cup when South Korea defeated the Philippines 1-0 in Dubai in the other Group C game.In Group D, another favorite, Iran, routed Yemen 5-0.FEATURED STORIESSPORTSPrivate companies step in to help SEA Games hostingSPORTSUrgent reply from Philippine ‍football chiefSPORTSWin or don’t eat: the Philippines’ poverty-driven, world-beating pool starsChina entered the Asian Cup with one win in seven games, including draws against Palestine, India, and Bahrain. It didn’t look much better at the start of Monday’s match.Akhlidin Israilov gave Kyrgyzstan the lead with a low left-foot shot from outside the box just before halftime. SEA Games hosting troubles anger Duterte LATEST STORIES View commentscenter_img Time to move on: Chris Tiu retires from basketball TS Kammuri to enter PAR possibly a day after SEA Games opening Don’t miss out on the latest news and information. MOST READ SEA Games: Biñan football stadium stands out in preparedness, completion The in-form Son is still with his Tottenham club for one more English Premier League match against Manchester United on Sunday before joining South Korea. He could be away for up to five of Tottenham’s matches in all competitions if South Korea reaches the final on Feb. 1 in Abu Dhabi.South Korea reached the final at the previous Asian Cup.In Abu Dhabi, two first-half goals from Mehdi Taremi helped Iran ease past Yemen.Iran is seeking a fourth title, with former Real Madrid and Portugal coach Carlos Queiroz in charge of Asia’s top-ranked team.Sports Related Videospowered by AdSparcRead Next LOOK: Joyce Pring goes public with engagement to Juancho Triviño But five minutes into the second half, Kyrgyzstan goalkeeper Pavel Matiash jumped to handle what seemed to be an easy catch following a corner kick. He was under no pressure with two of his teammates around him, but the ball went into the net off his gloves.Yu Dabao then angled in a left-footer in the 78th minute to ensure the fourth straight victory for China in its Asian Cup opening game and improve its record against Kyrgyzstan to 3-0.A runner-up in 1984 and 2004, China faces the Philippines and South Korea in its remaining group games.In Dubai, the Philippines had only 18 percent possession against the 2015 Asian Cup runner-up but managed to hold firm until the 67th minute.With forward Son Heung-min absent, Hwang Ui-jo scored the lone goal for South Korea.ADVERTISEMENTlast_img read more

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Scramble for Olympic tickets in Japan; rest of world waits

first_imgOrganizers extended the application period by 12 hours, citing high demand.Overseas residents will have to wait until June 15, when tickets can be put on sale by special distributors in each country — known as Authorized Ticket Resellers.FEATURED STORIESSPORTSPrivate companies step in to help SEA Games hostingSPORTSPalace wants Cayetano’s PHISGOC Foundation probed over corruption chargesSPORTSSingapore latest to raise issue on SEA Games food, logisticsOrganizers estimate 7.8 million tickets will be available, with 20-30% dedicated to sales outside Japan.This is the first phase of sales in Japan, with other chances available as the games get closer. Catholic schools seek legislated pay hike, too Tokyo organizers say 50 percent of the tickets will sell for 8,000 yen ($70) or less, with the cheapest ticket costing 2,500 yen ($22).Organizers hope to generate about $800 million from ticket sales, a large source of revenue for the $5.6 billion privately funded operating budget. Overall, Japan will spend about $20 billion to prepare for the games, and about 70 percent is public money.Japan recently passed a law that bans selling tickets at above the original prices. Violators face fines of up to 1 million yen ($9,100), or a one-year jail term — or both.The International Olympic Committee was embarrassed in Rio de Janeiro when IOC member Patrick Hickey was arrested and charged with ticket scalping, which is also illegal in Brazil. He denied any wrongdoing.Sports Related Videospowered by AdSparcRead Next ‘Rebel attack’ no cause for concern-PNP, AFP Private companies step in to help SEA Games hosting Player of the Week: Ray Parks taking Blackwater to new heights Trending Articles PLAY LIST 00:50Trending Articles00:45Onyok Velasco see bright future for PH boxing in Olympics00:59Sports venues to be ready in time for SEA Games02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games02:11Trump awards medals to Jon Voight, Alison Krauss Fans earlier this month complained to soccer governing body FIFA about buying tickets for next month’s Women’s World Cup in France, and then learning that friends and family were not given seats together.The same thing can happen buying Olympic tickets.CoSport says on its website that it cannot guarantee seats together.“While CoSport will make every effort to seat parties together, it is not possible to guarantee that all tickets for a given session and seating category will be seated together,” the company said.It also warns that tickets are sold by price category, not by exact seat location.Buyers outside Japan might get some deals if they are patient. It happened at the 2016 Olympics in Rio de Janeiro, and also at the Winter Olympics in Pyeongchang a year ago.Tokyo organizers will open sales globally in the spring of 2020, meaning any remaining, unsold tickets can be purchased at the prices offered in Japan. In Rio de Janeiro, many tickets were unsold as the games neared, and some desirable tickets were put back into the pool after they were sold but never paid for.Ticket prices in Japan vary greatly and are listed in the competition section on the organizers’ website.The opening ceremony on July 24 features the most expensive ticket — 300,000 yen ($2,680). The most expensive ticket for the closing ceremony is 220,000 yen ($1,965).The most expensive ticket for the men’s 100-meter final is 130,000 ($1,160), while the men’s basketball final goes for 108,000 yen ($970). DA eyes importing ‘galunggong’ anew FILE – In this June 20, 2016, file photo, a man handles the Olympic tickets he just purchased at a shopping mall in Rio de Janeiro, Brazil. Tokyo Olympic organizers say millions of Japan residents have shown interest in buying tickets for next year’s games. Organizers closed the first phase of ticket applications on Wednesday, May 29, 2019, for Japan residents, and applicants will be told on June 20 what tickets they have been allocated through a lottery system.(AP Photo/Silvia Izquierdo, File)TOKYO — The scramble is underway by residents of Japan to land tickets for next year’s Tokyo Olympics. It begins for the rest of the world in a few weeks.Tokyo Olympic organizers said millions had shown interest by Wednesday when the first phase of ticketing closed for Japan residents. Applicants will learn on June 20 what tickets they were allocated in a lottery system.ADVERTISEMENT MOST READ LATEST STORIES Ethel Booba twits Mocha over 2 toilets in one cubicle at SEA Games venue Tokyo Organizers on Wednesday declined to say how many tickets had been applied for through the on-line system. They say only that 7.5 million “ID registrations” have been recorded, which allowed people to apply and enter the lottery.“Tokyo 2020 is not disclosing additional details at this stage,” organizers said in a statement.Buying tickets in Japan is not cheap. But it’s more expensive outside Japan where the resellers — appointed by each national Olympic Committee — can add a 20% percent “handling fee” to the cost of each ticket.In addition, many tickets are packaged by resellers with top hotels and other perks, and the markups can be more than 20%. Many of these packages are aimed at corporate buyers, for whom price is not always a concern. The resellers also run the risk of getting stuck with tickets they can’t sell.The reseller for the United States is CoSport , which also handles sales in Australia, Jordan and several European countries.ADVERTISEMENT Cayetano: Senate, Drilon to be blamed for SEA Games mess PDEA chief backs Robredo in revealing ‘discoveries’ on drug war Don’t miss out on the latest news and information. Two-day strike in Bicol fails to cripple transport View commentslast_img read more

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SCOTS Corporate Touch Day

first_imgThe SCOTS PGC College inaugural Corporate Touch Day was held at Kearney Springs Sporting Complex in Toowoomba last Sunday. The carnival was a fundraising event for the College’s Touch Football tour to New Zealand in September and the support from McInnes Wilson Lawyers, Elders Real Estate Emerald, Blades, Australian Fresh Salads, Fuji Xerox Business Centre Toowoomba and Proterra Group was greatly appreciated.Director of Activities, Mr Andy McGregor Lowndes said, despite the cold weather the day was successful and everyone enjoyed themselves.  “16 teams competed on the day and all games were played in great spirit. The $5000 prize money attracted some very strong teams with six current Australian players who recently defeated New Zealand in the Trans Tasman Series playing on the day,” he said.  Teams travelled from Brisbane, Beenleigh and the Gold Coast. The $5000 Cup Final was won by the Tigers, defeating 2Fresh in the final 7-3.Kertisha Thompson (Watch the Feet) won the $1000 ladies ‘Dash for Cash’ and Sam Brisby (Tigers) won the $1000 men’s ‘Dash for Cash’.  Sam was one of four current Australian Men’s players participating at the carnival and was awarded ‘Player of the Cup Final’.Other results included the Plate final won by Back to Basics against Honey Badgers 4-3, the Bowl final with Recognition Plus defeating Federal Hotel 10-2 and the Shield Final Mad C’s beat McCormack’s Mean Machine 4-1.Acting Principal of The SCOTS PGC College, Mr Ben Manifold thanked the Toowoomba Touch Association and the referees, some of whom travelled from Brisbane, for their support to ensure the highest level of organisation and officiating possible. The SCOTS PGCC College will host its annual Secondary Schools Invitational Touch Carnival on July 27 which is expected to again attract over 50 teams.Related LinksScots Corporate Daylast_img read more

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10 months agoMurillo: Mina advice key to Barcelona move

first_imgMurillo: Mina advice key to Barcelona moveby Carlos Volcano10 months agoSend to a friendShare the loveJeison Murillo admits Yerry Mina convinced him about moving to Barcelona.Mina left Barca for Everton last summer and urged his Colombia teammate to accept the move when the Catalans approached Valencia about a loan deal.Murillo was unveiled by Barca yesterday and he confirmed Mina’s influence.”I am very friendly with Yerry. He recommended to me several things, he advised me,” said the defender.Murillo has joined Barca on-loan to June with a permanent option. TagsTransfersAbout the authorCarlos VolcanoShare the loveHave your saylast_img

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10 months agoChelsea have not signed Pulisic as Hazard replacement – Honigstein

first_imgTagsTransfersAbout the authorFreddie TaylorShare the loveHave your say Chelsea have not signed Pulisic as Hazard replacement – Honigsteinby Freddie Taylor10 months agoSend to a friendShare the loveChelsea signing Christian Pulisic is not a direct replacement for Eden Hazard, according to German football expert Ralph Honigstein.The American completed a move to Stamford Bridge on Wednesday and has been immediately loaned back to Borussia Dortmund for the rest of the 2018-19 season.Many Chelsea fans have feared Pulisic’s signing means Hazard will leave the club this summer. But Honigstein doesn’t think that is the case.”I’m not sure what this means for Hazard but he is not, at least not in my mind, a direct replacement,” he said.”He can play in the same positions of course but he is not going to add those goals necessarily.”He will provide plenty of assists and keep the ball, but I don’t see him filling the role that Hazard has – basically becoming both Chelsea’s playmaker and major goalscorer in the absence of a more prolific centre forward. I think we have to look at this move in isolation.” last_img read more

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Video: 2 High School Football Players Speared A Referee On Purpose

first_imgThree footballs next to a pylon(Photo by Streeter Lecka/Getty Images)Two high school football players are in some serious trouble, if we’re to believe that what you see in the below video was done on purpose.According to Deadspin, during a game between Marble Falls and San Antonio John Jay on Friday night, two high school defensive backs (who play for John Jay) targeted an official during live play. One speared him, just before the other dove into him, helmet-first. It’s one of the most ridiculous videos you’ll ever see.The title of the video suggests that it was in retaliation for a “bad call.” If that’s the case, this is reprehensible.Both players were ejected from the contest, and the district is investigating the play.last_img

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Opinion Ohio State regains top form with JT Barrett starting

OSU redshirt sophomore quarterback J.T. Barrett (16) runs with the ball during a game against Rutgers on Oct. 24 at High Point Solutions Stadium. OSU won, 49-7. Credit: Samantha Hollingshead / Photo EditorAfter Saturday’s 49-7 win against Rutgers, it is apparent that redshirt sophomore quarterback J.T. Barrett has earned his starting position within the offensive unit.Ohio State coach Urban Meyer announced last week the news of Barrett starting over redshirt junior Cardale Jones for the first time in the 2015 season. Barrett was able to take the reins in the 2014 season as the previous starter, Braxton Miller, was injured before the season even began.Barrett went 11-1 as the starting quarterback before he was injured with a broken ankle in the fourth quarter against Michigan on Nov. 29 while the Buckeyes led 28-21. Jones then stepped into the starting position leading the Buckeyes through three major wins, one being the National Championship.After the celebration of the team’s success had finally settled down, the two quarterbacks geared up for one of the most publicized quarterback battles in college football history.The decision to claim one starter above the other seemed inevitable to all fans, but when it came down to it, the coaches had a much tougher decision, as both Jones and Barrett have a multitude of valuable qualities that they bring to the field.Jones’ confidence on and off the field gave him the ability to lead the Buckeyes to a 10-0 record as the starting quarterback. Meanwhile, Meyer has described Barrett as a “humble perfectionist,” which is shown through his leadership, as evidenced by the fact that he was voted as a captain this season.While both quarterbacks have different attributes that allow them to shine, the decision to claim one over the other as starter just didn’t seem possible. Within the first seven games for the Buckeyes, both Jones and Barrett saw significant time, allowing both athletes to make a case for why each deserves the big spot. With the OSU offense looking in disarray, the coaching staff looked for an answer, and they found it against Penn State.It wasn’t until the “Dark Night at the ‘Shoe” that the decision was clear. Barrett went from the red zone quarterback to taking over for Jones full time in the second half. Winning 38-10 over Penn State revealed the high-powered Buckeyes we all remember from the 2014 season.After Barrett was named the starting quarterback following his performance against Penn State, the stage was set for the game against Rutgers. He proved himself more than worthy of the starting position by leading the Buckeyes to their most impressive blowout of a lesser opponent this season. Barrett led the Buckeyes to a 49-7 win in which he had 324 total yards of offense, with three passing touchdowns and two rushing touchdowns.The Buckeyes’ offense finally revealed what the defending champions’ fans have been waiting to see this season. As the Buckeyes took the field with their new starting quarterback it was as if a sense of rejuvenation, readiness and confidence had been draped upon them; the team was and now is more ready than ever before.With Barrett leading the charge, we all witnessed the best game performed by OSU thus far.Although it may be eight games into the season, the Buckeyes finally look like they have a vision in mind for a second straight championship. As the captain led the team to victory, one can conclude that, with Barrett in the starting position, the Buckeyes have a bright future ahead. read more

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